Identification of early stage recurrence endometrial cancer biomarkers using bioinformatics tools

Adjuvant Management of Early Stage Endometrial Cancer

Identification of Metabolomic Biomarkers for Endometrial Cancer and Its Recurrence after Surgery in Postmenopausal Women

Endometrial cancer (EC) is the most frequent gynecological cancer in developed countries. Most EC occurs after menopause and is diagnosed as endometrioid (type I) carcinomas, which exhibit a favorable prognosis. In contrast, non-endometrioid (type II) carcinomas such as serous tumors have a poor prognosis. Our goal was to identify novel blood-based markers associated with EC subtypes and recurr...

Adjuvant radiotherapy in early stage endometrial cancer.

OBJECTIVE To compare the rates of overall survival (OS), disease-free survival (DFS) and toxicity in different techniques of postoperative radiotherapy for stage IA endometrioid adenocarcionoma of endometrium, histological grades 1and 2. METHODS A historical comparison between treatment regimens was performed, and 133 women with a minimum follow-up of 5 years were included. Teletherapy (TELE ...

Prognostic biomarkers in early-stage prostate cancer.

EK There are 4 biopsy-based biomarker tests on the market for men who have not undergone surgery: Oncotype DX prostate cancer test from Genomic Health, Decipher Biopsy from GenomeDx, Prolaris from Myriad Genetics, and ProMark from Metamark Genetics (Table). The way they work is that a biopsy sample is sent to the company laboratory, which analyzes the expression of various genes in the prostate...

Identification of potential biomarkers of sepsis using bioinformatics analysis

Sepsis is defined as the systemic inflammatory response to infection and is one of the leading causes of mortality in critically ill patients. The goal of the present study is to elucidate the molecular mechanism of sepsis. Transcription profile data (GSE12624) were downloaded that had a total of 70 samples (36 sepsis samples and 34 non-sepsis samples) from the Gene Expression Omnibus database....